Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study
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Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study.
BACKGROUND Previous data support the benefits of reducing dietary saturated fatty acids (SFAs) on insulin resistance (IR) and other metabolic risk factors. However, whether the IR status of those suffering from metabolic syndrome (MetS) affects this response is not established. OBJECTIVE Our objective was to determine whether the degree of IR influences the effect of substituting high-saturat...
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Subjects with the metabolic syndrome (MetS) have enhanced oxidative stress and inflammation. Dietary fat quality has been proposed to be implicated in these conditions. We investigated the impact of four diets distinct in fat quantity and quality on 8-iso-PGF2α (a major F2-isoprostane and oxidative stress indicator), 15-keto-13,14-dihydro-PGF2α (15-keto-dihydro-PGF2α, a major PGF2α metabolite a...
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The changes of serum insulin in response to resistance training with emphasis on FOXO1 in pancreas of diabetes rats
Introduction: Decreased insulin sensitivity and its secretion of pancreas increase the risk of developing type 2 diabetes (T2D). In the present study it was aimed to assess the effect of resistance training on Forkhead box protein O1 (FOXO1) expression in pancreas tissue, serum insulin, and insulin sensitivity in obese rats with T2D. Materials and Methods: T2D was induced by high fa...
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ژورنال
عنوان ژورنال: The American Journal of Clinical Nutrition
سال: 2015
ISSN: 0002-9165,1938-3207
DOI: 10.3945/ajcn.115.111286